Analysis of signaling, cell cycle regulation, transcriptional regulation, and apoptosis. Molecular biology of GI-cancers
We are investigating the molecular biology of GI-cancers, with a special focus on pancreatic cancer, by the use of various in vitro and in vivo techniques. We are analyzing signaling pathways (NF-kappaB, PI3K) and molecular mechanisms of cell cycle control, apoptosis, and trancription. Furthermore, we explore therapeutic resistance mechanisms of cancer cells.