PhD Student Position in the Nawroth Group (Urology) Available

** UPDATE NOV 8th - the position has been filled **

The Department of Urology is offering a 3-year position (TVL-E13 65%) to a candidate with master or diploma thesis in life science/biology with extensive experience in molecular and cell biology.

The research topic is the identification of genes that are differentially regulated upon combination of oncolytic virus and CDK4/6 inhibitors and characterization of the underlying mechanism.

The department has developed a novel combination therapy including the oncolytic adenovirus XVir-N-31 and CDK4/6 inhibitors (PMID: 35948546). This therapy is currently being tested in a phase I clinical trial funded by the BMBF. In order to analyze genes that are differentially expressed in the combination therapy compared to monotherapy, cancer cells were treated in a time kinetic and analyzed by next generation sequencing.
The successful candidate will be tasked with identifying changes in the cellular and also the viral transcriptome. In a next step, functional verification and also characterization of genes that are differentially regulated shall result in a better understanding of the molecular mechanism underlying the effects on adenoviral replication and thus potency of the therapy.

The qualities and skills they are looking for:

  • Scientific rigor and curiosity
  • Excellent communication skills in German (fluent) and English
  • Ability to work in an international team

Please send your questions and/or job applications (with the CV, motivation letter, certificates) to roman.nawroth (at)